LIAISON Folate

Part of the B complex of vitamins, Folate is generic term for a group of water-soluble compounds and enzymatic cofactors (B9). It is critical in the metabolism of nucleic acid precursors and several amino acids, as well as in methylation reactions and is necessary for normal red blood cell formation. Folate deficiency (together with B12 deficiency) is the main cause of megaloblastic anaemia. If serum folate is low, also Vitamin B12 has to be assessed to exclude concurrent vitamin B12 deficiency before correcting the level of folate.

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LIAISON Folate